Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells. [electronic resource]
Producer: 20110913Description: 3198-206 p. digitalISSN:- 1476-5594
- Bone Marrow Cells -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cytokines -- metabolism
- Down-Regulation -- genetics
- Humans
- Immediate-Early Proteins -- deficiency
- Janus Kinases -- metabolism
- Multiple Myeloma -- genetics
- Protein Serine-Threonine Kinases -- deficiency
- RNA Interference
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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