Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer. [electronic resource]
Producer: 20110715Description: 2978-87 p. digitalISSN:- 1538-7445
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Base Sequence
- Cell Line, Tumor
- Cisplatin -- pharmacology
- Colorectal Neoplasms -- drug therapy
- Cytochromes b -- genetics
- DNA, Mitochondrial -- genetics
- DNA-Binding Proteins -- genetics
- Down-Regulation
- Frameshift Mutation
- HCT116 Cells
- Humans
- Mice
- Mice, Nude
- Microsatellite Instability
- Mitochondrial Proteins -- genetics
- Transcription Factors -- genetics
- Transcription, Genetic
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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