Enforced expression of the apoptosis inhibitor Bcl-2 ablates tolerance induction in DNA-reactive B cells through a novel mechanism. [electronic resource]
Producer: 20110928Description: 18-27 p. digitalISSN:- 1095-9157
- Animals
- Antibodies, Antinuclear -- blood
- Apoptosis -- genetics
- Autoantigens -- immunology
- Autoimmunity -- genetics
- B-Lymphocytes -- immunology
- DNA -- blood
- DNA-Binding Proteins -- antagonists & inhibitors
- Epitopes -- immunology
- Female
- Gene Expression Regulation -- genetics
- Immune Tolerance -- genetics
- Immunization
- Immunologic Memory -- genetics
- Mice
- Mice, Inbred BALB C
- Mice, Transgenic
- Molecular Mimicry -- immunology
- Peptides -- chemical synthesis
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Spleen -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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