Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection. [electronic resource]
Producer: 20110728Description: 18890-902 p. digitalISSN:- 1083-351X
- Acquired Immunodeficiency Syndrome -- drug therapy
- Antimicrobial Cationic Peptides -- biosynthesis
- Apoptosis Regulatory Proteins -- metabolism
- Autophagy -- drug effects
- Autophagy-Related Protein 12
- Autophagy-Related Protein 5
- Autophagy-Related Protein 7
- Beclin-1
- Cholecalciferol
- Dose-Response Relationship, Drug
- HIV-1 -- physiology
- Humans
- Macrophages
- Membrane Proteins -- metabolism
- Microtubule-Associated Proteins -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- RNA Interference -- drug effects
- Small Ubiquitin-Related Modifier Proteins -- metabolism
- Ubiquitin-Activating Enzymes -- metabolism
- Virus Replication -- drug effects
- Vitamins -- pharmacology
- Cathelicidins
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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