Disruption of HLA-DR raft, deregulations of Lck-ZAP-70-Cbl-b cross-talk and miR181a towards T cell hyporesponsiveness in leprosy. [electronic resource]
Producer: 20110616Description: 1178-90 p. digitalISSN:- 1872-9142
- Adaptor Proteins, Signal Transducing -- metabolism
- Adolescent
- Adult
- Cholesterol -- metabolism
- Clonal Anergy -- immunology
- Disease Progression
- Female
- HLA-DR Antigens -- immunology
- Histocompatibility Antigens Class II -- immunology
- Humans
- Leprosy -- immunology
- Leukocyte Common Antigens -- metabolism
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck) -- metabolism
- Macrophages -- microbiology
- Male
- Membrane Fluidity -- immunology
- Membrane Microdomains -- immunology
- MicroRNAs -- metabolism
- Middle Aged
- Mycobacterium leprae -- immunology
- Protein Isoforms -- metabolism
- Proto-Oncogene Proteins c-cbl -- metabolism
- Receptors, Antigen, T-Cell -- immunology
- Signal Transduction -- immunology
- T-Lymphocytes -- immunology
- ZAP-70 Protein-Tyrosine Kinase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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