Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. [electronic resource]
Producer: 20110722Description: 3625-34 p. digitalISSN:- 1538-7445
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Apoptosis Regulatory Proteins -- metabolism
- Autophagy
- Beclin-1
- Caspase 8 -- metabolism
- Cell Line, Tumor
- Cytochromes c -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Membrane Proteins -- metabolism
- Mice
- Mice, Nude
- Mutation
- Neoplasm Transplantation
- Neoplasms -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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