Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes. [electronic resource]
Producer: 20110909Description: 726-36 p. digitalISSN:- 1520-5010
- Agaricales -- chemistry
- Alkylation
- Antineoplastic Agents -- pharmacology
- Antioxidants -- metabolism
- Cell Survival -- drug effects
- Cysteine -- metabolism
- Enzyme Inhibitors -- pharmacology
- Glutathione Peroxidase -- antagonists & inhibitors
- HeLa Cells
- Humans
- Neoplasms -- drug therapy
- Polycyclic Sesquiterpenes
- Selenocysteine -- metabolism
- Sesquiterpenes -- pharmacology
- Spiro Compounds -- pharmacology
- Thioredoxin-Disulfide Reductase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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