Inhibition of HIF prolyl hydroxylase-2 blocks tumor growth in mice through the antiproliferative activity of TGFβ. [electronic resource]
Producer: 20110809Description: 3306-16 p. digitalISSN:- 1538-7445
- Animals
- Bone Neoplasms -- enzymology
- Cell Growth Processes -- physiology
- Cell Line, Tumor
- Female
- Gene Knockdown Techniques
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Hypoxia-Inducible Factor-Proline Dioxygenases
- Melanoma, Experimental -- enzymology
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Neoplasms, Experimental -- enzymology
- Osteosarcoma -- enzymology
- Procollagen-Proline Dioxygenase -- antagonists & inhibitors
- RNA, Small Interfering -- administration & dosage
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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