Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans. [electronic resource]
Producer: 20110715Description: 1701-14 p. digitalISSN:- 1525-2191
- Adrenal Cortex Hormones -- pharmacology
- Animals
- Autoantibodies -- chemistry
- Chromosome Mapping
- Hereditary Autoinflammatory Diseases -- genetics
- Homozygote
- Humans
- Immunoglobulins -- chemistry
- Inflammation
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mutation
- Neutrophils -- metabolism
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- genetics
- Skin Diseases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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