LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. [electronic resource]
Producer: 20110809Description: 5532-40 p. digitalISSN:- 1528-0020
- Adoptive Transfer
- Animals
- Antigens, CD -- genetics
- Antigens, Surface -- genetics
- Apoptosis Regulatory Proteins -- deficiency
- B7-1 Antigen -- genetics
- B7-H1 Antigen
- Bone Marrow Transplantation -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- CD40 Ligand -- antagonists & inhibitors
- CD8-Positive T-Lymphocytes -- immunology
- CTLA-4 Antigen
- Female
- Immune Tolerance
- Membrane Glycoproteins -- deficiency
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Models, Immunological
- Peptides -- deficiency
- Programmed Cell Death 1 Ligand 2 Protein
- Programmed Cell Death 1 Receptor
- Signal Transduction -- immunology
- Transforming Growth Factor beta -- immunology
- Transplantation, Homologous
- Lymphocyte Activation Gene 3 Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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