ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo. [electronic resource]
Producer: 20110624Description: 831-44 p. digitalISSN:- 1531-8249
- Age Factors
- Amyloid beta-Protein Precursor -- genetics
- Amyloidogenic Proteins -- drug effects
- Animals
- Brain -- drug effects
- Cathepsin D -- metabolism
- Cell Line, Tumor
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay -- methods
- Humans
- Indans -- pharmacology
- Macaca fascicularis
- Maze Learning -- drug effects
- Memory -- drug effects
- Mice
- Mice, Transgenic
- Molecular Weight
- Neuroblastoma -- pathology
- Peptide Fragments -- metabolism
- Proteomics -- methods
- Reaction Time -- drug effects
- Schizophrenia -- drug therapy
- Spiro Compounds -- pharmacology
- Subcellular Fractions -- drug effects
- Transfection
- Tubulin -- metabolism
- tau Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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