Redox active copper chelate overcomes multidrug resistance in T-lymphoblastic leukemia cell by triggering apoptosis. [electronic resource]
Producer: 20110930Description: 1701-12 p. digitalISSN:- 1742-2051
- Animals
- Antibiotics, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Line
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cells, Cultured
- Copper -- chemistry
- Cytochromes c -- metabolism
- Dose-Response Relationship, Drug
- Doxorubicin -- pharmacology
- Drug Resistance, Multiple -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Flow Cytometry
- Glutathione -- metabolism
- Glycine -- analogs & derivatives
- Humans
- Mice
- NIH 3T3 Cells
- Organometallic Compounds -- chemistry
- Oxidation-Reduction -- drug effects
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- metabolism
- Reactive Oxygen Species -- metabolism
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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