Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms. [electronic resource]
Producer: 20110719Description: 572-8 p. digitalISSN:- 2042-7158
- Alanine Transaminase -- blood
- Animals
- Antioxidants -- pharmacology
- Apoptosis -- drug effects
- Aspartate Aminotransferases -- blood
- Caspase 3 -- metabolism
- Catalase -- blood
- Disease Models, Animal
- Galactosamine
- Glutathione -- blood
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Lipopolysaccharides
- Liver Failure, Acute -- chemically induced
- Male
- Malondialdehyde -- blood
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Pentacyclic Triterpenes
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Signal Transduction -- drug effects
- Survival Analysis
- Triterpenes -- pharmacology
- Up-Regulation -- drug effects
- Betulinic Acid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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