Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents. [electronic resource]
Producer: 20110606Description: 2012-21 p. digitalISSN:- 1520-4804
- Antineoplastic Agents -- chemical synthesis
- Biological Products -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Topoisomerases, Type I -- metabolism
- DNA Topoisomerases, Type II -- metabolism
- Humans
- Inhibitory Concentration 50
- Topoisomerase II Inhibitors -- chemical synthesis
- Uracil -- chemical synthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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