Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. [electronic resource]
Producer: 20110816Description: 3085-96 p. digitalISSN:- 1527-7755
- Adult
- Antineoplastic Agents -- pharmacology
- DNA Mutational Analysis
- Disease Progression
- Drug Resistance, Neoplasm -- genetics
- Fatal Outcome
- Gene Expression Profiling
- Humans
- Indoles -- pharmacology
- MAP Kinase Kinase 1 -- genetics
- Male
- Melanoma -- drug therapy
- Mutation
- Phosphatidylethanolamine Binding Protein -- genetics
- Precision Medicine -- methods
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins B-raf -- genetics
- Skin Neoplasms -- drug therapy
- Sulfonamides -- pharmacology
- Vemurafenib
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Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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