Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. [electronic resource]
Producer: 20110801Description: e1001308 p. digitalISSN:- 1553-7404
- Adaptor Proteins, Signal Transducing -- genetics
- Aged
- Alzheimer Disease -- genetics
- Apolipoproteins E -- genetics
- CELF Proteins
- Case-Control Studies
- Clusterin -- genetics
- Family
- Gene Frequency -- genetics
- Genetic Predisposition to Disease
- Genome, Human -- genetics
- Genome-Wide Association Study
- Heterozygote
- Humans
- Middle Aged
- Nerve Tissue Proteins -- genetics
- Nuclear Proteins -- genetics
- Polymorphism, Single Nucleotide -- genetics
- Population Dynamics
- Principal Component Analysis
- Protein Binding
- RNA-Binding Proteins -- genetics
- Reproducibility of Results
- Tumor Suppressor Proteins -- genetics
- White People -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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