A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells. [electronic resource]
Producer: 20110725Description: 98-107 p. digitalISSN:- 1879-0712
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Biocatalysis -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Topoisomerases, Type II -- metabolism
- Down-Regulation -- drug effects
- Flavonoids -- chemical synthesis
- Free Radical Scavengers -- chemical synthesis
- Humans
- Male
- Molsidomine -- analogs & derivatives
- Oxidative Stress -- drug effects
- Prostatic Neoplasms -- metabolism
- Reactive Oxygen Species -- metabolism
- Topoisomerase II Inhibitors -- chemical synthesis
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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