Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents. [electronic resource]
Producer: 20110617Description: 1762-78 p. digitalISSN:- 1520-4804
- Aflatoxin B1
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Cells, Cultured
- Cytoprotection
- Enzyme Induction
- Heme Oxygenase-1 -- biosynthesis
- Interferon-gamma -- pharmacology
- Liver -- drug effects
- Liver Neoplasms, Experimental -- chemically induced
- Macrophages -- drug effects
- Male
- Mice
- NAD(P)H Dehydrogenase (Quinone) -- biosynthesis
- Nitric Oxide Synthase Type II -- antagonists & inhibitors
- Nitriles -- chemical synthesis
- Pentacyclic Triterpenes -- chemistry
- Phenanthrenes -- chemical synthesis
- Precancerous Conditions -- chemically induced
- Rats
- Stereoisomerism
- Stomach -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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