Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition. [electronic resource]
Producer: 20110617Description: 1643-9 p. digitalISSN:- 1527-7755
- Adolescent
- Child
- Child, Preschool
- Europe
- Female
- Gene Dosage
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Leukemic
- Gene Rearrangement, T-Lymphocyte
- Genes, T-Cell Receptor -- genetics
- Genetic Predisposition to Disease
- Homozygote
- Humans
- Male
- Mutation
- Neoplasms, Second Primary -- genetics
- New South Wales
- Oligonucleotide Array Sequence Analysis
- Oncogene Proteins, Fusion -- genetics
- Phenotype
- Polymorphism, Single Nucleotide
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Receptor, Notch1 -- genetics
- Recurrence
- Tennessee
- Time Factors
- Treatment Outcome
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Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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