Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. [electronic resource]
Producer: 20110505Description: 163-74 p. digitalISSN:- 1097-4180
- Amino Acid Substitution
- Animals
- Base Sequence
- Cell Cycle
- DNA Breaks, Double-Stranded
- DNA Repair
- DNA-Binding Proteins -- deficiency
- Female
- Gene Knock-In Techniques
- Gene Rearrangement
- Genes, p53
- Genomic Instability
- Lymphoma, Non-Hodgkin -- genetics
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phosphorylation
- Protein Processing, Post-Translational
- Receptors, Antigen, T-Cell -- genetics
- S-Phase Kinase-Associated Proteins -- genetics
- Specific Pathogen-Free Organisms
- T-Lymphocytes -- metabolism
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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