mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif. [electronic resource]
Producer: 20110628Description: 14190-8 p. digitalISSN:- 1083-351X
- Amino Acid Motifs
- Animals
- Cell Line
- Gene Expression Regulation, Enzymologic
- Humans
- Mice
- Models, Biological
- Phosphorylation
- Proteasome Endopeptidase Complex -- metabolism
- Protein Binding
- Proto-Oncogene Proteins c-akt -- metabolism
- Serine -- chemistry
- Signal Transduction
- TOR Serine-Threonine Kinases -- metabolism
- Trans-Activators -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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