Propofol inhibits lipopolysaccharide-induced lung epithelial cell injury by reducing hypoxia-inducible factor-1alpha expression. [electronic resource]
Producer: 20110516Description: 590-9 p. digitalISSN:- 1471-6771
- Acute Lung Injury -- chemically induced
- Anesthetics, Intravenous -- pharmacology
- Animals
- Apoptosis -- drug effects
- Cells, Cultured
- Cytokines -- biosynthesis
- Disease Models, Animal
- Drug Evaluation, Preclinical -- methods
- Endotoxemia -- chemically induced
- Epithelial Cells -- drug effects
- Gene Expression Regulation -- drug effects
- Gene Knockdown Techniques
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- biosynthesis
- Lipopolysaccharides
- Lung -- metabolism
- Mice
- Mice, Inbred BALB C
- Propofol -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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