Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. [electronic resource]
Producer: 20110815Description: 1738-50 p. digitalISSN:- 1460-2083
- Active Transport, Cell Nucleus
- Animals
- Cell Line
- Cell Nucleus -- genetics
- Disease Models, Animal
- Drosophila -- genetics
- HEK293 Cells
- Humans
- Intracellular Space -- genetics
- Karyopherins -- genetics
- Neurodegenerative Diseases -- genetics
- Peptides -- genetics
- Protein Binding
- Protein Structure, Tertiary
- Protein Transport
- Proteins -- chemistry
- Receptors, Cytoplasmic and Nuclear -- genetics
- Trinucleotide Repeat Expansion
- Exportin 1 Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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