Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1. [electronic resource]
Producer: 20110414Description: 2951-6 p. digitalISSN:- 1091-6490
- Allosteric Regulation -- physiology
- Animals
- Antithrombins -- metabolism
- Calcium -- metabolism
- Cell Line
- Dogs
- Epinephrine
- Flow Cytometry
- Luciferases
- P-Selectin -- metabolism
- Peptide Fragments -- metabolism
- Platelet Aggregation
- Protein Structure, Secondary -- physiology
- Receptor, PAR-1 -- agonists
- Receptors, G-Protein-Coupled -- metabolism
- Signal Transduction -- physiology
- Thrombosis -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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