β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells. [electronic resource]
Producer: 20110516Description: 2998-3005 p. digitalISSN:- 1550-6606
- Adaptor Proteins, Signal Transducing -- physiology
- Animals
- CD18 Antigens -- physiology
- Calcium Signaling -- immunology
- Cell Degranulation -- immunology
- Cell Line
- Cell Polarity -- immunology
- Cells, Cultured
- Cytoplasmic Granules -- immunology
- Drosophila melanogaster
- GPI-Linked Proteins -- physiology
- Humans
- Intercellular Adhesion Molecule-1 -- metabolism
- Intracellular Signaling Peptides and Proteins -- metabolism
- Killer Cells, Natural -- cytology
- Lymphocyte Activation -- immunology
- Membrane Proteins -- physiology
- Paxillin -- physiology
- Perforin -- metabolism
- Phospholipase C gamma -- metabolism
- Phosphorylation -- immunology
- Protein Binding -- immunology
- Protein-Tyrosine Kinases -- metabolism
- Receptors, Antigen, T-Cell -- metabolism
- Receptors, IgG -- physiology
- Syk Kinase
- Tyrosine -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Intramural
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