Zoledronic acid inhibits RANK expression and migration of osteoclast precursors during osteoclastogenesis. [electronic resource]
Producer: 20110729Description: 297-308 p. digitalISSN:- 1432-1912
- Acid Phosphatase -- metabolism
- Animals
- Bone Marrow Cells -- cytology
- Bone Resorption -- metabolism
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Diphosphonates -- pharmacology
- Diterpenes -- pharmacology
- Dose-Response Relationship, Drug
- Gene Expression -- drug effects
- I-kappa B Proteins -- metabolism
- Imidazoles -- pharmacology
- Isoenzymes -- metabolism
- Macrophages -- cytology
- Mice
- Mice, Inbred Strains
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Osteoclasts -- cytology
- Phosphorylation -- drug effects
- Protein Prenylation -- drug effects
- RANK Ligand -- pharmacology
- Receptor Activator of Nuclear Factor-kappa B -- genetics
- Signal Transduction -- drug effects
- Stem Cells -- cytology
- Tartrate-Resistant Acid Phosphatase
- Transcription, Genetic -- drug effects
- Tumor Necrosis Factor-alpha -- pharmacology
- Up-Regulation -- drug effects
- Zoledronic Acid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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