Lactone form 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) stimulate the osteoblastic differentiation of mouse periodontal ligament cells via the ERK pathway. [electronic resource]
Producer: 20110628Description: 204-13 p. digitalISSN:- 1600-0765
- Alkaline Phosphatase -- analysis
- Animals
- Anthraquinones
- Blotting, Western
- Bone Morphogenetic Protein 2 -- analysis
- Butadienes -- pharmacology
- Calcification, Physiologic -- drug effects
- Cell Culture Techniques
- Cell Differentiation -- drug effects
- Cell Line
- Cell Survival -- drug effects
- Coloring Agents
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Integrin-Binding Sialoprotein -- analysis
- Lovastatin -- pharmacology
- Mice
- Mitogen-Activated Protein Kinase 1 -- drug effects
- Nitriles -- pharmacology
- Osteoblasts -- drug effects
- Osteocalcin -- analysis
- Periodontal Ligament -- cytology
- Promoter Regions, Genetic -- drug effects
- Simvastatin -- pharmacology
- Transcriptional Activation -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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