A comparative study of the CYP450 inhibition potential of marketed drugs using two fluorescence based assay platforms routinely used in the pharmaceutical industry. [electronic resource]
Producer: 20110509Description: 30-9 p. digitalISSN:- 1874-0758
- Automation
- Cell Line
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- genetics
- Dose-Response Relationship, Drug
- Drug Discovery -- methods
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Escherichia coli -- enzymology
- Fluorescence
- High-Throughput Screening Assays -- methods
- Humans
- Microsomes -- drug effects
- Molecular Probes
- Recombinant Proteins -- antagonists & inhibitors
- Reproducibility of Results
- Substrate Specificity
- Technology, Pharmaceutical -- methods
- Transfection
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Publication Type: Comparative Study; Journal Article
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