Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascades. [electronic resource]
Producer: 20110412Description: 99 p. digitalISSN:- 1742-2094
- Animals
- Cell Line
- Enzyme Inhibitors -- metabolism
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- I-kappa B Proteins -- metabolism
- Inflammation -- chemically induced
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Lipopolysaccharides -- pharmacology
- MAP Kinase Kinase Kinases -- metabolism
- Mice
- Microglia -- cytology
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- RNA Interference
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- physiology
- Tumor Necrosis Factor-alpha -- metabolism
- Mitogen-Activated Protein Kinase Kinase Kinase 11
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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