In vivo 6-thioguanine-resistant T cells from melanoma patients have public TCR and share TCR beta amino acid sequences with melanoma-reactive T cells. [electronic resource]
Producer: 20110318Description: 76-86 p. digitalISSN:- 1872-7905
- Adult
- Aged
- Amino Acid Motifs
- Amino Acid Sequence
- Antigens, Neoplasm -- genetics
- Antineoplastic Agents -- pharmacology
- Biomarkers, Tumor -- genetics
- Case-Control Studies
- Cells, Cultured
- Drug Resistance, Neoplasm -- genetics
- Female
- Genes, T-Cell Receptor beta
- Humans
- Hypoxanthine Phosphoribosyltransferase -- deficiency
- Lymphocyte Activation
- Male
- Melanoma -- drug therapy
- Melanoma-Specific Antigens -- genetics
- Middle Aged
- Molecular Sequence Data
- Mutation
- Receptors, Antigen, T-Cell, alpha-beta -- genetics
- T-Lymphocytes -- drug effects
- Thioguanine -- pharmacology
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
There are no comments on this title.
Log in to your account to post a comment.