PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo. [electronic resource]
Producer: 20120914Description: 85-96 p. digitalISSN:- 1573-7217
- Animals
- Antineoplastic Agents -- chemistry
- Breast Neoplasms -- drug therapy
- Cell Adhesion -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Metastasis
- Phosphorylation -- drug effects
- Protein Binding
- Protein Kinase Inhibitors -- chemistry
- Purines -- chemistry
- Signal Transduction -- drug effects
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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