CCL19-induced chemokine receptor 7 activates the phosphoinositide-3 kinase-mediated invasive pathway through Cdc42 in metastatic squamous cell carcinoma of the head and neck. [electronic resource]
Producer: 20110509Description: 729-37 p. digitalISSN:- 1791-2431
- Adult
- Aged
- Aged, 80 and over
- Carcinoma -- genetics
- Carcinoma, Squamous Cell
- Cell Movement -- drug effects
- Chemokine CCL19 -- metabolism
- Drug Evaluation, Preclinical
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Head and Neck Neoplasms -- genetics
- Humans
- Male
- Middle Aged
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Neoplasms, Squamous Cell -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- RNA, Small Interfering -- pharmacology
- Receptors, CCR7 -- agonists
- Signal Transduction -- drug effects
- Squamous Cell Carcinoma of Head and Neck
- Tumor Cells, Cultured
- cdc42 GTP-Binding Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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