CREB is a regulatory target for the protein kinase Akt/PKB in the differentiation of pancreatic ductal cells into islet β-cells mediated by hepatocyte growth factor. [electronic resource]
Producer: 20110214Description: 711-6 p. digitalISSN:- 1090-2104
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Cell Differentiation
- Cells, Cultured
- Cyclic AMP Response Element-Binding Protein -- genetics
- Hepatocyte Growth Factor -- metabolism
- Insulin-Secreting Cells -- cytology
- Male
- Nerve Tissue Proteins -- genetics
- Pancreatic Ducts -- cytology
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- RNA, Small Interfering -- genetics
- Rats
- Rats, Wistar
- Signal Transduction
- Transcription Factors -- genetics
- Transcriptional Activation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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