Computer--based drug design, synthesis and biological evaluation of new pyrimidinone derivatives linked to arylpiperazine and 2'-carbethoxy-biphenylylmethyl moeities as alpha1-adrenoceptor antagonists and angiotensin II AT1 receptor antagonists. [electronic resource]
Producer: 20110110Description: 794-800 p. digitalISSN:- 0031-7144
- Adrenergic alpha-1 Receptor Antagonists -- chemical synthesis
- Angiotensin II Type 1 Receptor Blockers -- chemical synthesis
- Animals
- Biphenyl Compounds -- chemical synthesis
- Blood Pressure -- drug effects
- Computer Simulation
- Computer-Aided Design
- Drug Design
- Indicators and Reagents
- Models, Molecular
- Piperazines -- chemistry
- Protein Conformation
- Pyrimidines -- chemical synthesis
- Pyrimidinones -- chemical synthesis
- Rats
- Software
- Structure-Activity Relationship
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.