The legumain protease-activated auristatin prodrugs suppress tumor growth and metastasis without toxicity. [electronic resource]
Producer: 20110614Description: 54-9 p. digitalISSN:- 1860-7187
- Aminobenzoates -- administration & dosage
- Animals
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cysteine Endopeptidases -- metabolism
- Disease Models, Animal
- Enzyme Activation -- drug effects
- Female
- Humans
- Mice
- Neoplasm Metastasis -- drug therapy
- Oligopeptides -- administration & dosage
- Prodrugs -- administration & dosage
- Tumor Burden -- drug effects
- Weight Loss -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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