pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs. [electronic resource]
Producer: 20110427Description: e15455 p. digitalISSN:- 1932-6203
- Antigens, Surface -- genetics
- Antimetabolites, Antineoplastic -- pharmacology
- Blotting, Western
- Cell Line, Tumor
- Cell Proliferation
- Deoxycytidine -- analogs & derivatives
- Deoxycytidine Kinase -- genetics
- Drug Resistance -- genetics
- ELAV Proteins
- ELAV-Like Protein 1
- HEK293 Cells
- Humans
- Pancreatic Neoplasms -- genetics
- Protein Binding
- RNA Interference
- RNA, Messenger -- genetics
- RNA-Binding Proteins -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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