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  2. Details for: Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
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Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. [electronic resource]

By:
  • Ray, Peter
Contributor(s):
  • Wright, Jane
  • Adam, Julia
  • Bennett, Johnathan
  • Boucharens, Sylviane
  • Black, Darcey
  • Cook, Andrew
  • Brown, Angus R
  • Epemolu, Ola
  • Fletcher, Dan
  • Haunso, Anders
  • Huggett, Margaret
  • Jones, Phil
  • Laats, Steven
  • Lyons, Amanda
  • Mestres, Jordi
  • de Man, Jos
  • Morphy, Richard
  • Rankovic, Zoran
  • Sherborne, Brad
  • Sherry, Lorcan
  • van Straten, Nicole
  • Westwood, Paul
  • Zaman, Guido Z R
Producer: 20110414Description: 97-101 p. digitalISSN:
  • 1464-3405
Subject(s):
  • Amines -- chemical synthesis
  • Animals
  • Binding Sites
  • Computer Simulation
  • Crystallography, X-Ray
  • Drug Evaluation, Preclinical
  • Isoquinolines -- chemical synthesis
  • Mice
  • Mice, Inbred C57BL
  • Protein Kinase Inhibitors -- chemical synthesis
  • Structure-Activity Relationship
  • rho-Associated Kinases -- antagonists & inhibitors
Online resources:
  • Available from publisher's website
In: Bioorganic & medicinal chemistry letters vol. 21
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Publication Type: Journal Article

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Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.

APA

Ray P., Wright J., Adam J., Bennett J., Boucharens S., Black D., Cook A., Brown A. R., Epemolu O., Fletcher D., Haunso A., Huggett M., Jones P., Laats S., Lyons A., Mestres J., de Man J., Morphy R., Rankovic Z., Sherborne B., Sherry L., van Straten N., Westwood P. & Zaman G. Z. R. (20110414). Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. : Bioorganic & medicinal chemistry letters.

Chicago

Ray Peter, Wright Jane, Adam Julia, Bennett Johnathan, Boucharens Sylviane, Black Darcey, Cook Andrew, Brown Angus R, Epemolu Ola, Fletcher Dan, Haunso Anders, Huggett Margaret, Jones Phil, Laats Steven, Lyons Amanda, Mestres Jordi, de Man Jos, Morphy Richard, Rankovic Zoran, Sherborne Brad, Sherry Lorcan, van Straten Nicole, Westwood Paul and Zaman Guido Z R. 20110414. Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. : Bioorganic & medicinal chemistry letters.

Harvard

Ray P., Wright J., Adam J., Bennett J., Boucharens S., Black D., Cook A., Brown A. R., Epemolu O., Fletcher D., Haunso A., Huggett M., Jones P., Laats S., Lyons A., Mestres J., de Man J., Morphy R., Rankovic Z., Sherborne B., Sherry L., van Straten N., Westwood P. and Zaman G. Z. R. (20110414). Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. : Bioorganic & medicinal chemistry letters.

MLA

Ray Peter, Wright Jane, Adam Julia, Bennett Johnathan, Boucharens Sylviane, Black Darcey, Cook Andrew, Brown Angus R, Epemolu Ola, Fletcher Dan, Haunso Anders, Huggett Margaret, Jones Phil, Laats Steven, Lyons Amanda, Mestres Jordi, de Man Jos, Morphy Richard, Rankovic Zoran, Sherborne Brad, Sherry Lorcan, van Straten Nicole, Westwood Paul and Zaman Guido Z R. Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. : Bioorganic & medicinal chemistry letters. 20110414.

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