A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF. [electronic resource]
Producer: 20110317Description: 404-12 p. digitalISSN:- 1538-7445
- HEK293 Cells
- HeLa Cells
- Histone Deacetylase 1 -- metabolism
- Humans
- Kruppel-Like Transcription Factors -- genetics
- N-Myc Proto-Oncogene Protein
- Nerve Growth Factor -- pharmacology
- Nerve Tissue Proteins -- biosynthesis
- Neuroblastoma -- genetics
- Nuclear Proteins -- genetics
- Oncogene Proteins -- genetics
- Promoter Regions, Genetic
- Protein Structure, Tertiary
- Receptor, trkA -- biosynthesis
- Receptors, Nerve Growth Factor -- biosynthesis
- Sp1 Transcription Factor -- genetics
- Transcription, Genetic
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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