Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities. [electronic resource]
Producer: 20110328Description: 191-200 p. digitalISSN:- 1768-3254
- Acrylates -- chemical synthesis
- Animals
- Anti-Inflammatory Agents -- chemical synthesis
- Antioxidants -- chemical synthesis
- Binding Sites
- Cyclooxygenase 1 -- chemistry
- Cyclooxygenase Inhibitors -- chemical synthesis
- Drug Design
- Female
- Free Radical Scavengers -- chemical synthesis
- Inflammation -- drug therapy
- Lipoxygenase -- chemistry
- Lipoxygenase Inhibitors -- chemical synthesis
- Male
- Models, Molecular
- Protein Conformation
- Rats
- Glycine max -- enzymology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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