Heparin changes the conformation of high-mobility group protein 1 and decreases its affinity toward receptor for advanced glycation endproducts in vitro. [electronic resource]
Producer: 20110425Description: 187-93 p. digitalISSN:- 1878-1705
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemistry
- Biosensing Techniques
- Cell Line
- Circular Dichroism
- Cytokines -- immunology
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- Glycation End Products, Advanced -- chemistry
- HMGB1 Protein -- chemistry
- Heparin -- chemistry
- Humans
- Macrophages -- drug effects
- Mice
- Protein Binding
- Protein Conformation
- Spectrometry, Fluorescence
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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