Pegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin. [electronic resource]
Producer: 20110621Description: 506-12 p. digitalISSN:- 1600-0641
- Active Transport, Cell Nucleus -- drug effects
- Animals
- Antiviral Agents -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Gene Knockdown Techniques
- Hep G2 Cells
- Hepatitis C, Chronic -- complications
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Interferon alpha-2
- Interferon-alpha -- pharmacology
- Liver -- drug effects
- Liver Neoplasms -- drug therapy
- Mice
- Mice, Transgenic
- Mutant Proteins -- genetics
- Nuclear Proteins -- antagonists & inhibitors
- Nucleocytoplasmic Transport Proteins -- antagonists & inhibitors
- Polyethylene Glycols -- pharmacology
- RNA, Small Interfering -- genetics
- Recombinant Proteins -- genetics
- Signal Transduction -- drug effects
- Transcription, Genetic -- drug effects
- Wnt Proteins -- metabolism
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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