The E2A-HLF oncogenic fusion protein acts through Lmo2 and Bcl-2 to immortalize hematopoietic progenitors. [electronic resource]
Producer: 20110408Description: 321-30 p. digitalISSN:- 1476-5551
- Adaptor Proteins, Signal Transducing
- Animals
- Cell Survival
- Cell Transformation, Neoplastic
- DNA-Binding Proteins -- genetics
- Hematopoietic Stem Cells -- metabolism
- Humans
- LIM Domain Proteins
- Leukemia -- etiology
- Metalloproteins -- genetics
- Mice
- Oncogene Proteins, Fusion -- genetics
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Retroviridae
- Transcription Factors -- genetics
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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