Pifithrin-α, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway. [electronic resource]
Producer: 20110411Description: 313-9 p. digitalISSN:- 1423-0313
- Benzothiazoles -- administration & dosage
- Breast Neoplasms -- pathology
- Cell Line, Tumor
- Cells, Cultured
- Cyclooxygenase 2 -- genetics
- Dose-Response Relationship, Drug
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Female
- Fibroblasts
- Humans
- MAP Kinase Kinase Kinases -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphorylation -- drug effects
- Toluene -- administration & dosage
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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