The flavonoid quercetin transiently inhibits the activity of taxol and nocodazole through interference with the cell cycle. [electronic resource]
Producer: 20110308Description: 1025-35 p. digitalISSN:- 1532-7914
- Antineoplastic Agents, Phytogenic -- metabolism
- Cell Adhesion
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin B1 -- metabolism
- Food-Drug Interactions
- G2 Phase -- drug effects
- Humans
- Microtubules -- drug effects
- Neoplasms -- drug therapy
- Nocodazole -- antagonists & inhibitors
- Osmolar Concentration
- Paclitaxel -- antagonists & inhibitors
- Quercetin -- metabolism
- Time Factors
- Tubulin -- metabolism
- Tubulin Modulators -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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