Bioinspired total synthesis and human proteasome inhibitory activity of (-)-salinosporamide A, (-)-homosalinosporamide A, and derivatives obtained via organonucleophile promoted bis-cyclizations. [electronic resource]
Producer: 20110422Description: 2-12 p. digitalISSN:- 1520-6904
- Antineoplastic Agents -- chemical synthesis
- Catalysis
- Crystallography, X-Ray
- Cyclization
- Humans
- Lactones -- chemical synthesis
- Magnetic Resonance Spectroscopy
- Molecular Conformation
- Molecular Structure
- Proteasome Endopeptidase Complex -- chemistry
- Proteasome Inhibitors
- Pyrroles -- chemical synthesis
- Stereoisomerism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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