Interferon-β induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK-STAT signaling and down-regulation of PI3K/Akt pathway. [electronic resource]
Producer: 20110104Description: 1421-33 p. digitalISSN:- 1471-4159
- Animals
- Apoptosis -- physiology
- Cell Line, Tumor
- Down-Regulation -- physiology
- Humans
- Interferon-beta -- physiology
- Janus Kinases -- metabolism
- Mice
- Neuroblastoma -- enzymology
- Phosphatidylinositol 3-Kinase -- physiology
- Phosphoinositide-3 Kinase Inhibitors
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- STAT1 Transcription Factor -- metabolism
- Signal Transduction -- physiology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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