P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer. [electronic resource]
Producer: 20110523Description: 1059-71 p. digitalISSN:- 1476-5594
- Animals
- Blotting, Western
- Breast Neoplasms -- metabolism
- Cell Movement
- Cell Proliferation
- Electrophoresis, Polyacrylamide Gel
- ErbB Receptors -- genetics
- Female
- Guanine Nucleotide Exchange Factors -- genetics
- Humans
- Immunoprecipitation
- Mice
- Mice, Nude
- Molecular Targeted Therapy
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Neuregulins -- genetics
- Oncogene Proteins v-erbB -- genetics
- Phosphorylation
- Prognosis
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- rac GTP-Binding Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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