TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection. [electronic resource]
Producer: 20110106Description: 132-40 p. digitalISSN:- 1096-0341
- Animals
- Antibodies, Monoclonal -- immunology
- CCR5 Receptor Antagonists
- CD3 Complex -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- Cell Line
- DNA, Viral -- analysis
- Down-Regulation
- Female
- Gene Products, gag -- genetics
- Humans
- Macaca mulatta
- Male
- Receptors, Antigen, T-Cell -- genetics
- Receptors, CCR5 -- genetics
- Simian Acquired Immunodeficiency Syndrome -- immunology
- Simian Immunodeficiency Virus -- pathogenicity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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