PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes. [electronic resource]
Producer: 20110531Description: 53 p. digitalISSN:- 1471-2172
- Cells, Cultured
- Chemokine CCL20 -- biosynthesis
- Chemokine CXCL5 -- biosynthesis
- Chemokines, CXC -- biosynthesis
- Down-Regulation
- Humans
- Immunity, Innate
- Keratinocytes -- immunology
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mouth -- pathology
- Periodontitis -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor, PAR-1 -- immunology
- Receptor, PAR-2 -- immunology
- Signal Transduction -- immunology
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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