Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. [electronic resource]
Producer: 20101230Description: 19449-54 p. digitalISSN:- 1091-6490
- Animals
- Carrier Proteins -- drug effects
- Inflammasomes -- drug effects
- Inhalation
- Interleukin-1alpha -- metabolism
- Interleukin-1beta -- metabolism
- Keratinocytes -- drug effects
- Mice
- NLR Family, Pyrin Domain-Containing 3 Protein
- Nanoparticles -- toxicity
- Pneumonia -- etiology
- Receptors, Interleukin-1 -- metabolism
- Signal Transduction -- immunology
- Silicon Dioxide -- toxicity
- Titanium -- toxicity
- Zinc Oxide
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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